平溃散治疗消化性溃疡临床研究的质量评价

Quality assessment for clinical research of Pingkuisan in the treatment of peptic ulcer.

目的评价平溃散治疗消化性溃疡临床研究论文的方法学质量。方法对相关文献8篇,按照Cochrane Reviewer’s handbook4.2.3评价指南的质量评价标准进行质量评价,分析。结果仅有3篇随机对照试验符合纳入标准,且均为半随机对照研究(CCT);3篇研究均为低质量的研究(C级),存在选择性偏倚、实施偏倚、测量偏倚及损耗性偏倚的高度可能性。结论要获得临床平溃散治疗消化性溃疡的可靠证据,尚需进行更多高质量的随机对照研究。

Objective To assess the quality of clinical research on Pingkuisan in the treatment of peptic ulcer.Methods The quality of 8 pertinent literatures was assessed and analyzed according to the quality assessment criteria in the evaluation manual of Cochrane Reviewer＇s handbook4.2.3.Results Only 3 literatures were up to the related standards,and all of the 3 studies were semi-randomized controlled trials（CCT）.All of the 3 studies were low quality（Grade C）researches,in which the biases on selectivity,practice,measurement and wastage were highly possible.Conclusion More randomized controlled trials of high quality are needed to reli able evidences on Pingkuisan in the treatment of peptic ulcer.