2型糖尿病足相关危险因素的临床分析

The Correlation risk factors analysis of diabetic foot in type 2 diabetic patients.

目的调查住院患者糖尿病足的危险因素指导临床更好防治糖尿病足,预防截肢。方法测定340例糖尿病患者,其中糖尿病足80例非糖尿病足260例,分析其一般资料,生化指标及并发症等。结果与非糖尿病足组比较,糖尿病足组在年龄、病程、体重指数、HbA1c、LDL-C,差异有统计学意义(P<0.05),而在性别、重度PAD(下肢动脉病变)、吸烟、FIB、收缩压高、周围神经病变、糖尿病肾病、视网膜病变,差异有统计学意义(P<0.01)。经多因素logistic回归分析显示:重度PAD、吸烟、收缩压高、周围神经病变、视网膜病变、FIB(纤维蛋白原)是糖尿病足的相关危险因素。结论糖尿病足的相关危险因素是重度PAD、吸烟、收缩压高、周围神经病变、视网膜病变、FIB。

Objective To study the risk factors of diabetic foot among inpatients.Methods Analysis the data including biochemical findings and complications between 80 diabetic patients with diabetic foot and 260 diabetic patients without.Results There are statistically significant differences in age,sex,course of disease,BMI,HbA1c,FIB,LDL-C,sever PAD（disease of lower extremity）、smoking、systolic blood pressure、neuropathy、diabetic nephropathy、retinopathy between group of diabetic foot and group without diabetic foot.Mulitple logistic regression analysis reveals sever PAD,smoking,an increased systolic blood pressure,neuropathy,retinopathy and FIB are risk factors associated with diabtic foot.Conclusion Risk factors for diabetic foot include advanced PAD,smoking,an increased systolic blood pressure,neuropathy,retinopathy and FIB.