高敏C反应蛋白检测对化脓性膝关节炎的临床价值

Clinical value of the high sensitive C-reactive protein (hs-CRP)in septic knee

目的探讨高敏C反应蛋白检测对化脓性膝关节炎诊治的临床价值。方法回顾46例入选患者高敏C反应蛋白、血沉、白细胞计数、中性粒细胞百分比结果 ,进行分析比较。结果①高敏C反应蛋白的敏感性高于白细胞计数、中性粒细胞百分比,与血沉差异无统计学意义(P>0.05)。②高敏C反应蛋白在不同程度的膝关节感染患者间的检测结果与其他各指标一样,差异无统计学意义(P>0.05)。③高敏C反应蛋白在患者症状改善前后的检测结果与其他各指标一样,差异无统计学意义(P>0.05)。④高敏C反应蛋白与血沉检测结果之间存在不强的正的直线相关关系(P<0.05)。结论高敏C反应蛋白检测在本研究中未显示出更高的临床价值。

Objective To investigate the clinical value of high sensitive C - reactive protein（ hs - CRP） in septic knee. Methods The results of hs - CRP, erythrocyte sedimentation rate （ ESR）, white blood cell count （ WBC）, neutrophile granulocyte percentage （NGP） of 46 septic knee cases were compared and analyzed retrospectively. Results The sensitivity of hs - CRP was higher than WBC and NGP, not higher than ESR. The same as other examinations, the levels of hs - CRP had not significant difference between the patients with different degree of synovial infection. None of the four examinations showed significant difference when symptoms relieve. There was weak positive linear correlation between hs - CRP and ESR. Conclusion High sensitive C - reactive protein doesn＇ t show higher clinical value in septic knee.