锡伯族和汉族冠心病患者颈动脉粥样硬化及冠状动脉病变对比分析

The Contrast Analysis of Carotid Atherosclerosis and Coronary Artery Lesion Between Xibo and Han Nationality Patients with Coronary Heart Disease

目的对比分析锡伯族、汉族冠心病患者颈动脉粥样硬化及冠状动脉病变情况。方法对经冠状动脉造影明确的48例锡伯族、57例汉族冠心病患者和50例正常对照者均行颈动脉超声检查,比较各组间颈动脉内膜中膜厚度、斑块的发生率及冠状动脉病变的Gensini积分。结果锡伯族、汉族冠心病患者内膜中膜厚度及颈动脉斑块的发生率均高于正常对照者(1.1±0.3mm和1.0±0.1mm比0.6±0.2mm、88.3%和77.2%比38.0%,P<0.05),但锡伯族与汉族间比较没有统计学差异(P>0.05);锡伯族患者冠状动脉病变支数少于汉族(1.82±0.24比2.54±0.31,P<0.05),冠状动脉病变的Gensini积分也明显低于汉族(8.23±1.35比15.84±2.68,P<0.05),且冠状动脉病变支数越多,锡伯族、汉族冠心病患者颈动脉粥样硬化程度越重。结论锡伯族和汉族冠心病患者颈动脉粥样硬化情况均重于正常对照者,但锡伯族和汉族间比较没有统计学意义;锡伯族和汉族冠心病患者冠状动脉病变存在差异,且锡伯族冠心病患者冠状动脉病变严重程度低于汉族;通过颈动脉内膜中膜厚度的程度可预测冠状动脉病变的存在及严重程度。

Aim To compare and analyze carotid atherosclerosis and coronary artery lesion between Xibo and Han patients with coronary heart disease. Methods Carotid ultrasound was performed in 48 Xibo,57 Han nationality patients and 50 normal controls who had been diagnosed by coronary angiography,then the intima-media thickness （IMT）,the prevalence rate of atherosclerotic and Gensini score of coronary artery lesion were compared. Results IMT and prevalence rate of atherosclerotic of Xibo and Han nationality patients were higher than the normal control group （1.1±0.3 mm and 1.0±0.1 mm vs 0.6±0.2 mm,88.3% and 77.2% vs 38.0%,P〈0.05）,but there was no significant difference between Xibo and Han nationality patients （P〉0.05）; The number of coronary artery lesion of Xibo nationality patients was less than Han nationality patients （1.82±0.24 vs 2.54±0.31,P〈0.05）; The Gensini score of coronary artery lesion of Xibo nationality patients was obviously less than Han nationality patients （8.23±1.35 vs 15.84±2.68,P〈0.05）. Furthermore,the more serious coronary artery lesion,the higher incidence rate of carotid atherosclerosis. Conclusions The carotid atherosclerosis of Xibo and Han nationality patients was serious than the normal control group,but there were no significant differences between Xibo and Han nationality patients; There were differences between Xibo and Han nationality patients about coronary artery lesion,and the coronary artery lesion of Han nationality patients was more serious than Xibo; The extent of IMT can reflect the occurrence and serious extent of coronary artery lesion.