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端粒酶对癌的早期检测 被引量:4

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摘要 端粒是真核生物染色体的天然末端,它对染色体的稳定起重要作用。其长度缩短或丢失可导致细胞老化。端粒酶是一种特殊的核糖核蛋白逆转录酶,它的活化可以自身RNA为模板合成端粒DNA加到染色体末端,从而维持端粒长度,使细胞永生。因此,端粒及端粒酶和恶性肿瘤间的关系成为近来研究热点。端粒酶激活有望成为癌的早期检测的生物学标记。
作者 关方霞
出处 《国外医学(耳鼻咽喉科学分册)》 1999年第1期7-10,共4页 Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
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