奥曲肽治疗非静脉曲张上消化道大出血疗效观察

Clinical observation of non-variceal upper gastrointestinal hemorrhage with octreotide

目的 探讨常规内科治疗与联合国产奥曲肽治疗非静脉曲张上消化道大出血的临床疗效.方法 将100例非静脉曲张上消化道大出血患者平均分成两组,A组为常规内科治疗,B组为常规内科治疗基础上联合国产奥曲肽首剂0.1 mg静脉注射后,再以奥曲肽25 μg/h微泵维持静注,出血控制24 h后停用.结果 联合奥曲肽组治疗非静脉曲张上消化道大出血疗效显著高于常规内科治疗组,有效止血率达98%,且不良反应少.结论 在常规内科治疗的基础上联合国产奥曲肽治疗非静脉曲张上消化道大出血止血快,疗效满意,不良反应少,价格合适,尤其适合基础疾病多的老年患者.

Objective The aim is to discuss the clinical effects of treating the invaricose upper gastrointestinal bleeding with regular medical treatment and regular treatment in combination with domestic - made octreotide. Methods We divide 100 patients with invaricosc gastrointestinal bleeding into 2 groups averagely. Group A for regular medical treatment,and group B for injecting domestic - made ectreotide based on regular medical treatment. After intravenous injection of 0. 1 mg domestic -made octreotide, maintain intravenousinjection of octreotide with 23 ug/h minipump. Stop injecting after controlling bleeding for 24 hours. Results The curative effect of the group using ectreotide in combination with regular medical treatment is significantly better than the gToup with medical treatment only. And the rate of stopping bleeding reaches 98%. It has little negative effects. Conclusion When treating the invaricose upper gastrointestinal bleeding, using domestic - made ectreotide based on regular medical treatment helps stop bleeding faster. The curative effect is satisfied and it has little negative effect. The price is reasonable. It is especially suitable for old patients with fundamental disease.