安定联合赖氨匹林直肠给药用于小儿高热惊厥急救临床观察

Clinical Observation the Curative Effect of Rectum Treatment on Children of Pyrogenic Eclampsia with Diazepam Combines Lysine Acetysalicyate

目的观察安定联合赖氨匹林溶液直肠给药治疗小儿高热惊厥的疗效。方法将40例高热惊厥患儿随机分为对照组19例和治疗组21例。治疗组直肠注入赖氨匹林和安定混合液（赖氨匹林20mg/kg,安定0.05mg/kg）,对照组给予赖氨匹林注射剂（20mg/kg）稀释后肌肉注射,安定注射液（剂量：0.5mg/kg,最大剂量不超过20mg）肌肉注射。比较两组在用药后5min、15min的止惊效果和30min、60min内的退热效果。结果治疗组的止惊效果和退热效果明显高于对照组（P〈0.01）,差异有统计学意义。结论安定联合赖氨匹林直肠给药用于治疗小儿高热惊厥,是静脉或口服给药困难时重要的替代途径,能有效保证高热惊厥的及时抢救。

Objective To observe curative effect of rectum Treatment on children of pyrogenic eclampsia with diazepam combines lysine acetylsalieylate . Method Dividing 40 cases pyrogenic eelampsia children into 19 cases of control group and 2.1 cases of treatment group. To pour in lysine aeetylsalieylate and diazepam mixture liquid on rectum in control group. Muscle inject after diluting lysine acetylsalicylate injection liquid （20mg/kg） in treatment group. Diazepam injection liquid （dose 0.5mg/kg,max dose less than 20mg） muscle injecting. Contrast cease eclampsia effective on 5,15min and defervesce effective within 30,60min in two groups after curing. Result Cease eclampsia effective and defervesce effective in treatment group obviously higher than control group （P〈0.01）.Discrepancy is of statistics significance. Conclusion Diazepam combines lysine acetylsalicylate curative effect of rectum Treatment on children of pyrogenic eclampsia is important substitute way when vein or take orally in difficulties.Which could effective guarantee promptly rescue of pyregenic eclampsia.