摘要
目的研究刺山柑果实的化学成分。方法通过硅胶、sephadex LH-20及反相硅胶(Rp-18)柱层析等色谱方法进行分离,根据理化性质和光谱数据进行结构鉴定。结果从刺山柑果实85%的乙醇提取物中分离鉴定了13个化合物,分别为:二氢-4羟基-5-羟甲基-2(3H)呋喃酮(1)、7-hydroxy-2-oxoindolin-3-ylaceticacid(2)、吲哚-3-甲醛(3)、尿嘧啶(4)、山柰酚芸香苷(5)、芦丁(6)、(6S)-hydroxy-3-oxo-a-ionol(7)、spionosideB(8)、β-谷甾醇(9)、β-胡萝卜苷(10)、β-胡萝卜苷-6′-硬脂酸酯(11)、肌醇(12)和尿苷(13)。结论化合物1~3,12和13为首次从该属植物中分离得到。
Objective To study the chemical constituents of the fruits of Capparis spinosa L. Methods The compounds were separated and purified by column chromatography and their structures were identified by spectroscopic methods. Results Thirteen compounds were isolated from the ethanol extracts of the fruits of C. spinosa L. The structures were determined as 4-hydroxy-5-[hydroxymethyl) dihydrofuran-2 ( 3 H )-one ( 1 ), 7-hydroxy-2-oxoindolin-3-ylacetic acid ( 2 ), 1 H-indole-3-carhaldehyde ( 3 ), uracil ( 4 ), kaempferol-3-O-rutinoside ( 5 ), rutin (6), ( 6 S )- Hydroxy-3-oxo-a-ionol ( 7 ), spionoside B ( 8 ), β-sitosterol ( 9 ), β-daucosterol ( 10 ), β-sitosterylglucoside-6'-octadecanoate( 11 ), myo-inositol( 12 ), and uridine( 13 ). Conclusion Compounds 1 - 3,12 and 13 were isolated from C. spinosa for the first time.
出处
《西北药学杂志》
CAS
2010年第4期260-263,共4页
Northwest Pharmaceutical Journal
基金
上海市教育委员会科研项目资助课题(05CZ31)
上海市重点学科建设资助项目(Y0301)资助
关键词
刺山柑
果实
化学成分
Capparis spinosa L.
fruits
chemical constituents