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痛风性关节炎及类风湿性关节炎患者血清hs-CRP水平的变化和意义 被引量:11

Changes and Significance of Serum hs-CRP Level in Patients with Gouty Arthritis or Rheumatoid Arthritis
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摘要 目的观察痛风性关节炎(gouty arthritis)及类风湿性关节炎(rheumatoid arthritis,RA)患者血清中超敏C反应蛋白(hypersensitive C reactive protein,hs-CRP)水平的变化。方法选择健康体检者42例为对照组,痛风性关节炎组30例,类风湿性关节炎组20例及高尿酸血症组40例用全自动生化分析仪分别检测血清中hs-CRP、UA、RF的水平并进行统计学分析。结果痛风性关节炎组及类风湿性关节炎组hs-CRP水平明显高于对照组(P<0.05),痛风性关节炎组hs-CRP水平明显高于高尿酸血症组(P<0.05)。结论 hs-CRP可作为痛风性关节炎和类风湿性关节炎的诊断指标之一。 Objective To observe the alteration of serum high sensitive O reactive protein (hs - CRP) level in patients with gouty arthritis or rheumatoid arthritis. Methods Automatic biochemistry analyzer was used to detect the levels of hs- CRP, uric acid, and rheumatoid factor in seraof 42 healthy controls, 30 patients with gouty arthritis, 20 patients with rheumatoid arthritis, and 40 patients with hyperuricemia. The results were statistically analyzed. Results The level of hs - CRP in sera of patients with gouty arthritis or rheumatoid arthritis was significantly higher than that of healthy controls (P〈 0.05). The level of hs- CRP in sera of patients with gouty arthritis was significantly higher than that of patients with hyperuricemia (P〈0.05). Conclusions hs - ORP can be used as one of the indicators for diagnosis of gouty arthritis and rheumatoid arthritis.
作者 孙际明
出处 《实用预防医学》 CAS 2010年第7期1427-1428,共2页 Practical Preventive Medicine
关键词 痛风 类风湿性关节炎 超敏C-反应蛋白 高尿酸血症 Gout Rheumatoid arthritis hs-CRP Hyperuricemia
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