无溶剂条件下的不对称催化反应

Asymmetric Catalytic Reactions under Solvent-Free Conditions

本文综述了近年来在无溶剂条件下进行的一些不对称催化反应的进展,着重介绍了无溶剂条件下的不对称Aldol反应、环氧化合物不对称开环反应、外消旋环氧化合物的拆分、不对称Diels-Alder反应、金属有机试剂对醛酮的不对称加成反应、不对称氢化反应、不对称氢甲酰化反应、不对称烯烃复分解反应、不对称Michael加成反应、不对称氧化反应、不对称Friedel-Crafts反应等,同时展望了无溶剂不对称催化反应的研究前景。

Recent developments in asymmetric catalytic reactions under solvent-free conditions were reviewed. The article mainly discussed asymmetric Aldol reaction, asymmetric ring-opening reaction, kinetic resolution of racemic epoxides, asymmetric Diels-Alder reaction, asymmetric addition of organometallic reagents to aldehydes and ketones, asymmetric hydrogenation, asymmetrichydroformylation, asymmetric metathesis reaction, asymmetric Michael addition reaction, asymmetric oxidation and asymmetric Friedel-Crafts reaction. The prospect of asymmetric catalytic reactions under solvent-free condition was also proposed.