老年食管癌手术前后生存质量的临床研究

Clinical study of quality of life during operation in elderly patients with esophageal cancer

目的探讨老年食管癌切除手术前后生存质量的变化情况。方法收集老年组(n=40)与非老年组(n=40)食管癌切除手术患者,通过QLQ-C30和QLQ-OES18量表对手术前后行生存质量调查。结果术后25天,老年组QLQ-C30各项生存质量指标与治疗前基线状态相比基本恢复,与非老年组比较,无显著性差异;而老年组QLQ-OES18中进食、梗阻、食欲减退、咳嗽等指标较非老年组显著降低,吞咽困难显著升高,于治疗40天,两组指标无显著性差异。结论老年食管癌手术前后生存质量通用量表QLQ-C30评分的变化与非老年组患者相近,而食管癌专用量表QLQ-OES18中部分指标的恢复较非老年患者需要更长的时间。

Objective To explore changes of quality of life during operation in elderly patients with esophageal cancer.Methods To investigate quality of life of 80 patients（elderly group was 40 patieuts and non-elderly group was 40 patieuts）by QLQ-C30 and QLQ-OES18 questionnaires.Results Compared with baseline status,global quality of life in QLQ-C30 scores in elderly group had no significant difference after 25 days of operation,when had no significant difference between elderly group and non-elderly group,as well as had significant difference in dysphagia,eating,obstruction,anorexia and cough between elderly group and non-elderly group,and had no significant difference after 40 days of operation.Conclusion There is no significant difference in QLQ-C30 scores between elderly patients and non-elderly patients with esophageal cancer,but it takes more time to reserve for some of QLQ-OES18 scores in elderly patients than that in non-elderly patients with esophageal cancer.