老年冠心病合并2型糖尿病患者冠状动脉造影特点分析

Coronary angiographic analysis of elderly patients with type 2 diabetes mellitus combined with coronary heart disease

目的通过冠状动脉造影,观察老年冠心病(CAD)合并2型糖尿病(T2DM)患者与无糖尿病患者冠状动脉病变程度的差异。方法分析2003年3月至2009年7月通过冠状动脉造影确诊CAD的487例老年患者,其中合并T2DM患者(DM组)212例、无T2DM患者(NDM组)275例,比较两组冠状动脉造影结果。结果 DM组冠状动脉狭窄程度、狭窄支数、狭窄长度明显高于NDM组,完全闭塞及弥漫性病变12例(5.7%)vs16例(7.5%),P<0.05,比例显著高于NDM组7例(2.5%)vs6例(2.2%),P<0.05。结论老年CAD合并T2DM患者,冠状动脉病变程度更重,完全闭塞、弥漫性病变较无T2DM冠心病患者更多见。

Objective To analyze the characteristic of coronary artery angiography between type 2 diabetes mellitus（T2DM）and non-diabetic patients with coronary arterial disease（CAD） in elderly patients. Methods A total of 487 elderly patients with coro- nary angiography confirmed coronary diseases, who were treated in People Hospital of Banan District during Mar. 2003 to Jul. 2009, were respectively analyzed. The patients were further divided into 2 subgroups according to the presence of T2DM：DM group （n：=212） and non-DM group （n=275）. The angiographic outcomes were analyzed and compared between the two groups. Results The stenosis extent, ramus,lenth in the DM group was significantly higher than that in the non-DM group （P^0.05）. The prevalence of total and diffusion lesions in diabetic group was 12（5.7 %） vs 1 6 （7. 5%, P〈 0.05）, significantly higher than that of non-diabetic group （7（2.5%） vs 6（2.2%） ,P〈（0.05）. Conclusion The extent and severity of angiographic coronary arterial disease is worse in coronary heart disease patients with type 2 diabetes than non-diabetic patients. Both the prevalence of total and diffusion lesions of coronary in the diabetics are higher than that in those without diabetes.