戴力新治疗功能性胃肠病109例疗效观察

Treatment effects of Deanxit for functional gastrointestinal disorders in 109 cases

目的探讨戴力新对功能性胃肠病(FGID)的治疗作用。方法选取我院186例FGID患者,分为治疗组和对照组,每组根据是否伴随焦虑抑郁等症状,以及患者为FD或IBS进行分组。治疗组在常规治疗的基础上加用戴力新,每次1片,每天早上及中午各1次;统计分析各组的有效率和无效率。结果在伴有明显精神症状的患者中,FD患者经戴力新治疗后有效率明显高于对照组,P<0.01;IBS患者治疗组有效率明显高于对照组,P<0.01。在不伴有精神症状但经常规治疗无效的FD患者治疗组有效率达75%,IBS患者治疗组有效率达68.7%。结论戴力新是治疗FGID患者的有效且安全的精神类药物,对于伴有明显抑郁或焦虑的FGID患者可在治疗初期即加用戴力新,对于不伴有抑郁或焦虑紧张但是经常规治疗无效的患者可加用戴力新治疗。

Objective To explore the treatment effects of Deanxit for functional gastrointestinal disorders（FGID）.Methods Totally 186 patients with FGID were selected and divided into treatment group and control group.Each group was divided again based on whether the patient was accompanied by anxiety and depression or whether the patient suffered form functional dyspepsia（FD）and irritable bowel syndrome（IBS）.For patients in treatment group,another piece of Deanxit was added.The effective rate and ineffective rate were analyzed.Results The effective rate of FD and IBS patients with anxiety and depression was obviously higher than those in control group（P0.01）.The effective rate of FD and IBS patients without anxiety and depression amounted to 75% and 68.7% respectively.Conclusion Deanxit is an effective and safe psychology drug for FGID.It can be administered to FGID patients with anxiety and depression at early stage and it is also effective for patients without anxiety and depression but resistent to conventional therapy.