2型糖尿病患者发作急性心肌梗死的临床特点和近期预后研究

Clinical Characteristics and Near-future Prognosis in T2DM Patients with Acute Myocardial Infarction

目的评价2型糖尿病患者发作急性心肌梗死的临床特点及近期预后。方法选取我院1993—2005年初发急性ST段抬高心肌梗死患者1056例,按照是否有糖尿病分为两组(糖尿病组和对照组),对比分析两组患者的临床特点、危险因素、住院并发症发生率和病死率。结果糖尿病组患者的年龄较高、心功能Killip分级I级者所占比例低,合并高血压的比例高、冠状动脉多支病变者所占比例高、病死率高,与对照组比较差异均有统计学意义(P<0.05)。结论合并糖尿病的心肌梗死患者年龄大、合并高血压的比例高、冠状动脉多支病变多见、心功能更差、住院期预后差。

Objective To investigate the clinical characteristics and in-hospital mortality in type 2 diabetes mellitus （T2DM） patients with acute myocardial infarction （AMI）.Methods A total of 1 056 primary patients with acute ST-segment elevation myocardial infarction from the year of 1993 to 2005 were divided,according to whether with diabetes,into groups diabetic,control.The clinical features,risk factors,in-hospital complication morbidity and mortality were compared between 2 groups.Results Diabetic patients,relatively old with a low proportion of heart function Killip I grade,and a higher proportion of combination with hypertension,coronary artery multi-vessel diseases and a higher mortality,were different significantly from control （ P〈 0.05） Conclusion The AMI patients complicated by diabetes are older with a higher proportion of combination with hypertension,and have commonly coronary artery multi-vessel diseases,worse heart function and poor in-hospital prognosis.