活血利水法治疗中心性浆液性脉络膜视网膜病变的临床研究

Clinical study of method of activating blood and diuresis on central serous chorioretiopathy

目的:观察活血利水法治疗中心性浆液性脉络膜视网膜病变的临床疗效。方法:对108例129眼中心性浆液性脉络膜视网膜病变患者采用在中医辨证论治基础上加以活血利水法治疗,肾虚证者采用补益肝肾、活血利水法,用杞菊地黄汤加减;脾虚湿泛证者采用健脾活血利水(湿)法,用参苓白术散加减;肝经郁热证者采用疏肝清热、活血利水法,用丹栀逍遥散加减;并与采用常规中医辨证论治105例124眼进行对照。结果:经1个疗程的治疗,治疗组临床治愈39眼,显效47眼,好转40眼,无效3眼,有效率97.7%;对照组临床治愈28眼,显效39眼,好转50眼,无效7眼,有效率94.4%。两组相比,差异有非常显著性意义(P<0.01)。两组患者经治疗后视力均明显提高,每组治疗前后比较,差异有非常显著性意义(P<0.01);经治疗后,治疗组和对照组相比较,差异亦有显著性意义(P<0.05)。结论:在中医辨证论治基础上加以活血利水法治疗,能提高中心性浆液性脉络膜视网膜病变的临床疗效、恢复患者有用视力。

AIM： To observe the effects of method of activating blood and diuresis on central serous chorioretiopathy. METHODS： One hundred and twenty-nine eyes in 108 cases with CSC were treated in the method of activating blood and diuresis on the basis of treatment with syndrome differentiation. Deficiency of kidney was treated in the method of tonifying liver and kidney, activating blood and diuresis and modification of Wolfberry,Chrysanthemum and Rehmania Decoction; Spleen dysfunction due to dampness was treated in the method of tonifying spleen and activating blood and diuresis and modification of Ginseng, Poria and Bighead Atractylodes Powder;Liver dysfunction due to heat was treated in the method of clearing heat, activating blood and diuresis, modified Merry Life Powder. These eyes were compared with 124 eyes in 105 cases treated in common treatment with syndrome differentiation. RESULTS： After one treatment period therapy group had cure effect in 39 eyes, markedly improvement in 47 eyes,improvement in 40 eyes, failure in 3 eyes, effective rate 97. 7%; control group had cure effect in 28 eyes, markedy improvement in 39 eyes, improvement in 50 eyes,failure in 7 eyes, effective rate 94.4%. Compared with twe groups,there was siganicant difference（ P 〈 0.01 ）. After two groups were treated their vision were improved. Compared before and after treatment of each group there was siganicant difference （ P 〈 0. 01 ）; after treatment compared therapy group with control group difference was statistically significant（ P〈 0.05）. CONCLUSION： The method can improve clinical effectand patients＇ vision on CSC on the basis of treatment with syndrome differentiation.