期刊文献+

Angiographic leakage of polypoidal choroidal vasculopathy on indocyanine angiography 被引量:5

Angiographic leakage of polypoidal choroidal vasculopathy on indocyanine angiography
原文传递
导出
摘要 Background There is no detailed report about the angiographic leakage of polypoidal choroidal vasculopathy (PGV) lesions on indocyanine green (ICG) angiography. This study aimed to investigate the angiographic leakage of polypoidal lesions in PCV on ICG angiography. Methods One hundred and forty-four eyes of 137 patients diagnosed as PCV were prospectively observed. Fundus examination, fluorescein angiography, and ICG angiography were performed. Leakage of polypoidal lesions and clinical features were recorded according to the angiograms. Results In all 144 eyes, 110 eyes showed angiographic leakage (leakage group) on ICG angiography and three subtypes of leakage group were noted, which were polypoidal dilations leakage (47 eyes, 42.7%), branching vascular networks leakage (14 eyes, 12.7%) and leakage of both (49 eyes, 44.5%). The other 34 eyes showed regression of polypoidal lesions (regression group). In leakage group, the rates of pigment epithelial detachment (PED), best corrected visual acuity (BCVA) 〈0.1 and old subretinal hemorrhages were 56.4% (62 eyes), 19.1% (21 eyes), and 4.6% (5 eyes) respectively, compared with 8.8% (3 eyes), 50% (17 eyes) and 38.2% (13 eyes) of regression group (P 〈0.001). The history of regression group was significantly longer (P 〈0.001). Conclusions Angiographic leakage and regression can be observed in PCV lesions. Leakage of both polypoidal dilations and branching vascular networks is the most common subtype in leakage group. PCV in leakage group is more likely to be related to PED, better BCVA and shorter history, while PCV regression group tends to relevant to old subretinal hemorrhage, worse BCVA and longer history. This may reflect that the former is active or in the early course while the later is resting or in the late phase of PCV. Background There is no detailed report about the angiographic leakage of polypoidal choroidal vasculopathy (PGV) lesions on indocyanine green (ICG) angiography. This study aimed to investigate the angiographic leakage of polypoidal lesions in PCV on ICG angiography. Methods One hundred and forty-four eyes of 137 patients diagnosed as PCV were prospectively observed. Fundus examination, fluorescein angiography, and ICG angiography were performed. Leakage of polypoidal lesions and clinical features were recorded according to the angiograms. Results In all 144 eyes, 110 eyes showed angiographic leakage (leakage group) on ICG angiography and three subtypes of leakage group were noted, which were polypoidal dilations leakage (47 eyes, 42.7%), branching vascular networks leakage (14 eyes, 12.7%) and leakage of both (49 eyes, 44.5%). The other 34 eyes showed regression of polypoidal lesions (regression group). In leakage group, the rates of pigment epithelial detachment (PED), best corrected visual acuity (BCVA) 〈0.1 and old subretinal hemorrhages were 56.4% (62 eyes), 19.1% (21 eyes), and 4.6% (5 eyes) respectively, compared with 8.8% (3 eyes), 50% (17 eyes) and 38.2% (13 eyes) of regression group (P 〈0.001). The history of regression group was significantly longer (P 〈0.001). Conclusions Angiographic leakage and regression can be observed in PCV lesions. Leakage of both polypoidal dilations and branching vascular networks is the most common subtype in leakage group. PCV in leakage group is more likely to be related to PED, better BCVA and shorter history, while PCV regression group tends to relevant to old subretinal hemorrhage, worse BCVA and longer history. This may reflect that the former is active or in the early course while the later is resting or in the late phase of PCV.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2010年第12期1548-1552,共5页 中华医学杂志(英文版)
关键词 CLASSIFICATION indocyanine green angiography polypidal choroidal vasculopathy classification indocyanine green angiography polypidal choroidal vasculopathy
  • 相关文献

参考文献21

  • 1Yannuzzi LA,Ciardella A,Spaide RF,Rabb M,Freund KB,Orlock DA.The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy.Arch Ophthalmol 1997;115:478-485.
  • 2Yannuzzi LA,Wong DW,Sforzolini BS,Goldbaum M,Tang KC,Spaide RF,et al.Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration.Arch Ophthalmol 1999; 117:1503-1510.
  • 3Lafaut BA,Leys AM,Snyers B,Rasquin F,De Laey JJ.Polypoidal choroidal vasculopathy in Caucasians.Graefes Arch Clin Exp Ophthalmol 2000; 238:752-759.
  • 4Spaide RF,Guyer DR,McCormick B,Yannuzzi LA,Burke K,Mendelsohn M,et al.External beam radiation therapy for choroidal neovascularization.Ophthalmology 1998; 105:24-30.
  • 5Guyer DR,Yannuzzi LA,Slakter JS,Sorenson JA,Hanutsaha P,Spaide RF,et al.Classification of choroidal neovascularization by digital indocyanine green videoangiography.Ophthalmology 1996; 103:2054-2060.
  • 6Obana A,Gohto Y,Matsumoto M,Miki T,Nishiguti K.Indocyanine green angiographic features prognostic of visual outcome in the natural course of patients with age related macular degeneration.Br J Ophthalmol 1999; 83:429-437.
  • 7Yannuzzi LA,Sorenson J,Spaide RF,Lipson B.Idiopathic polypoidal choroidal vasculopathy (IPCV).Retina 1990; 10:1-8.
  • 8Liu Y,Wen F,Huang S,Luo G,Yan H,Sun Z,et al.Subtype lesions of neovascular age-related macular degeneration in Chinese patients.Graefes Arch Clin Exp Ophthalmol 2007;245:1441-1445.
  • 9Sho K,Takahashi K,Yamada H,Wada M,Nagai Y,Otsuji T,et al.Polypoidal choroidal vasculopathy:incidence,demographic features,and clinical characteristics.Arch Ophthalmol 2003; 121:1392-1396.
  • 10Kwok AK,Lai TY,Chan CW,Neoh EL,Lam DS.Polypoidal choroidal vasculopathy in Chinese patients.Br J Ophthalmol 2002; 86:892-897.

同被引文献19

引证文献5

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部