炎症与动脉粥样硬化关系研究进展

The Progression of The Relation Between Inflammation and Atherosclerosis

研究表明动脉粥样硬化是一种慢性炎症,在内皮损伤、脂质代谢异常、血流动力学损伤、遗传、感染、物理化学等损伤刺激下,多种炎症因子、免疫机制及相关细胞因子网络交叉样作用于血管壁,形成慢性炎症。炎症反应贯穿于动脉粥样硬化的启动、形成和发展以及不稳定斑块,众多的的炎症标志物为动脉粥样硬化的评估和临床预测提供一条重要途径。抗炎症治疗在动脉粥样硬化的防治中不断取得突破。

Atherosclerosis is a chronic inflammation. Under the stimulation of endothelium injury, abnormality of lipid metabolism hemodynamics injury, heredity, inflammation and physical chemistry, chronic inflammtion of blood vessel can be informed by the effects of many kinds of inflammtory factors, immunologic mechnism and cytokines. Inflammation exist in the onset, formation, development and unstable plaque Mang inflammatory marker provide one important way for the evaluation ang clinical anticipation of atherosclerosis. Antiinflammatory therapy gets constant breakthrough in the prevention and cure of the atherosclerosis.