上海市老年期痴呆患病现况研究

A Cross-Sectional Study of Senile Dementia in Shanghai

目的了解上海市65岁及以上人群痴呆患病情况。方法运用分层随机整群抽样方法 ,以上海3个街道(镇)共计15158名65岁及以上老年人为调查对象,经过量表筛查和精神科医生确诊2个阶段,实施老年期痴呆的流行病学调查。结果简易智能精神状态检查量表(MMSE)筛查阳性率为9.9%;日常生活活动能力量表(ADL)阳性率为9.9%;有2306名老人作为可疑患者进入确诊流程;最终确诊老年期痴呆患者1271例,65岁及以上社区人群老年期痴呆粗患病率为8.1%,年龄标化后为6.1%,患病率与年龄、性别、受教育程度、婚姻状况有关(P<0.01)。结论老年期痴呆已成为危害老年人健康的重要疾病之一。

Objective To investigate the epidemiology of senile dementia in Shanghai.Methods 15158 residents aged 65 or over were selected by stratified random cluster sampling from 3 districts in Shanghai.Two stages was carried to ascertain dementia：in the first stage,Mini Mental State Examination （MMSE） and Activity of Daily Living Scale （ADL） were used as screening tools;in the second stage,DSM-Ⅳ criteria for dementia was applied to diagnosis.Results Screening positive rate of MMSE and ADL are both 9.9%.1271 cases of elderly with dementia were identified.The crude and age-standardized prevalence in residents aged 65 or over was 8.1% and 6.1%.The female,older age,lower education and worse marriage seemed to be more susceptible to senile dementia（P〈0.01）.Conclusion Senile dementia has become one of major diseases harmful to elderly＇s health.