男性尿道炎患者多形核白细胞计数与解脲脲原体感染的临床相关性分析

Clinical analysis of the relationship between polymorphonuclear leukocytes and Ureaplasma urealyticum infection in male patients with urethritis

本研究旨在检测男性尿道炎患者中尿道多形核白细胞数量,并进行解脲脲原体(Uu)培养,以评价非淋病奈瑟菌性尿道炎的临床意义。将2284例男性性病患者的尿道分泌物涂片,亚甲蓝(美蓝)染色后镜检多形核白细胞,并体外培养尿道分泌物的Uu。结果显示,645例患者(28.2%)Uu培养阳性,其中158例(24.5%)≥5个多形核白细胞,157例(24.3%)1～4个多形核白细胞,330例(51.2%)无多形核白细胞。218例阳性患者(33.8%)无症状,614例阳性患者(95.2%)无体征。男性尿道多形核白细胞数量在Uu培养阳性和阴性患者中存在显著差异(P<0.01)。结果提示临床诊断与实验室检查在证实男性非淋病奈瑟菌性尿道炎中具有重要意义。

In the current study,the polymorphonuclear leukocyte （PMNL） count as determined by methyl blue stain and Ureaplasma urealyticum （Uu） culture were used to determine the relationship between PMNL number and Uu infection in male patients with urethritis.A total of 2284 male patients seeking treatment for suspected sexually transmitted diseases were enrolled.The results showed that 645 （28.2%） patients had Uu infection.Among them,the number of PMNL per oil-immersion field was ≥5 in 158 （24.5%） cases,between 1 and 4 in 157 （24.3%） cases,and zero in 330 （51.2%） cases;218 （33.8%） and 614 （95.2%） cases had no symptoms or signs of infection.There was significant difference between PMNL number and Uu infection （P0.01）.These results indicate that both clinical diagnosis and laboratory testing are important for confirming nongonococcal urethritis in male patients.