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ⅡA分泌型磷脂酶A2与缺血性脑卒中的相关性研究

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摘要 ⅡA分泌型磷脂酶A2(ⅡA-sPLA2)是来源于正常动脉壁平滑肌细胞的一种既能分解磷脂、又在血液循环和动脉壁均有促动脉粥样硬化(AS)作用的磷脂酶,可修饰及水解脂蛋白,产生大量脂质介质及引发一系列慢性炎症反应,最终使细胞内脂类蓄积,导致AS。抑制ⅡA-sPLA2活性可能有抗AS的效应。在缺血性卒中的发病风险及预防性治疗上,ⅡA-sPLA2是一个新的有待研究的因子,本文就ⅡA-sPLA2与缺血性脑卒中的关系进行综述。
作者 张慧芳 王颖慧
机构地区 包头医学院 包头医学院第一附属医院神经内科
出处 《包头医学院学报》 CAS 2010年第3期132-133,共2页 Journal of Baotou Medical College
关键词 ⅡA分泌型磷脂酶A2 颈动脉粥样硬化 缺血性脑卒中
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献17

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包头医学院学报
2010年 第3期

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