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毕路Ⅱ式胃大部切除术对2型糖尿病的影响

Effect of Subtotal Gastrectomy Surgery on Type 2 Diabetes Mellitus
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摘要 目的:对毕路Ⅱ式胃大部切除术对2型糖尿病的影响及其作用机制的综述,探讨该术式是否可以成为治疗2型糖尿病的有效治疗方式。方法:复习文献,回顾分析毕路Ⅱ式胃大部切除术对继发性糖代谢和内分泌变化的影响。结果:毕路Ⅱ式胃大部切除术后,2型糖尿病患者的糖代谢改善率明显提高。结论:毕路Ⅱ式胃大部切除术对控制2型糖尿病有积极的影响。 Objective：To review the effect of subtotal gastrectomy surgery on type 2 diabetes mellitus and its working mechanism,to analyze data that might explain the mechanisms of action of this surgery and that could answer the question of whether surgery for morbid obesity can represent a cure for type 2 diabetes patients as well.Methods：the authors reviewed data from the literature to address.What is known about the effect of the operations for obesity on glucose metabolism and the endocrine changes that follow these operations？Results：After gastrectomy surgery on type 2 diabetes mellitus,a significant change happens in the patter of secretion of gastmintestinal hormones.Conclusion：Subtotal gastrectomy surgery on type 2 diabetes mellitus seems to achieve control of type 2 diabetes as good effect.
作者 侯晓倩 许斌
机构地区 辽宁中医药大学 辽宁中医药大学附属第四医院
出处 《辽宁中医药大学学报》 CAS 2010年第7期115-117,共3页 Journal of Liaoning University of Traditional Chinese Medicine
关键词 毕路Ⅱ式胃大部切除术 2型糖尿病 subtotal gastrectomy surgery type 2 diabetes mellitus
分类号 R781.64 [医药卫生—口腔医学]
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参考文献28

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  • 4PatritiA, AisaMC, Annetti C, et al. How the hindgut can cure type 2 diabetes. Ileal transposition improves glucose metabolismand beta cell function in Goto kakizaki rats through an enhanced Proglucagon gene expression and L cell number[ J ] .Surgery, 2007, 142 ( 1 ): 7428.
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二级参考文献28

  • 1Papadopoulos AA,Konlodimopoulos N,Frydas A, et al. Predictors of health-related quality of life in type Ⅱ diabetic patients in Greece [ J ]. BMC Public Health, 2007,7 ( 147 ) : 186.
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  • 5Schauer PR, lkramuddin S,Gourash W,et al. Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity[ J ]. Ann Surg, 2000,232 ( 4 ) : 515-529.
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  • 7Pories WJ,Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus [ J ]. Ann Surg, 1995,222 ( 3 ) :339-350.
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  • 9Patriti A, Aisa MC,Annetti C, et al. How tile hindgut can cure type 2 diabetes. Ileal transposition improves glucose metabolism and beta-cell function in Goto-kakizaki rats through an enhanced Proglucagon gene expression and L-cell number[ J]. Surgery, 2007,142( 1 ) :74-85.
  • 10MacDonald KG Jr, Long SD, Swanson MS, et al. The gastric bypass operation reduces the progression and mortality of non-insulin-dependent diabetes mellitus[ J ]. J Gastrointest Surg, 1997,1 ( 3 ) :213-220.

共引文献11

辽宁中医药大学学报
2010年 第7期

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