紫苏籽的超临界CO_2萃取及β-环糊精包合一体化技术研究

Study on Technology of Supercritical CO_2 Extraction of Perilla Oil and Its Integrated Inclusion with α-Cyclodextrin

采用超临界CO2流体萃取技术,研究紫苏油提取工艺条件,利用β-环糊精超临界微胶囊技术,研究紫苏油超临界包合一体化工艺条件。研究结果表明,制备紫苏油微胶囊的优化条件为:紫苏籽超临界萃取紫苏油的超临界压力23 MPa,β-环糊精最佳超临界包合压力12 MPa;包合反应时间180 min,包合反应温度55℃,萃取剂CO2流量40 L/min。按此条件制得的紫苏油环糊精包合物,α-亚麻酸包合率为16.37%,最高包合物质量分数为16.42%,最高包合比(β-环糊精与紫苏油物质的量比)达1.84∶1;平均包合物质量分数为13.94%,平均包合比1.55∶1。

Perilla oil was extracted with supercritical CO2 extraction,and the supercritical conditions for integrated inclusion of perilla oil was researched using β-cyclodextrin microcapsulation technology.The results show that the optimum conditions were： supercritical extraction pressure of perilla oil 23MPa,the optimum β-cyclodextrin inclusion supercritical pressure 12MPa,inclusion reaction time 180min,inclusion reaction temperature 55℃,extractant CO2 flow rate 40L/min.α-Lindenic acid inclusion rate is 16.37%,the maximum ratio of mass fraction of β-cyclodextrin/perilla oil is 16.42%,the highest molar complexation ratio（β-cyclodextrin/perilla oil） amounts to 1.84∶1（molar ratio of material）,average mass fraction of perilla oil/β-cyclodextrin is 13.94%,and the average complexation ratio is 1.55∶1（molar ratio of material）.