摘要
卟啉化合物具有特殊的理化性质和生理功能,已经成为研究热点之一。在卟啉分子中引入亲水基团例如羧基可以提高其水溶性。本文利用琥珀酸酐对单氨基四苯基卟啉进行了修饰,将一个羧基引入卟啉分子。采用核磁共振、红外光谱、紫外可见光谱等手段对产物进行了表征,实验结果为首次报道。元素分析所得结果与理论计算值一致。同时,报道了产物4-氧代-4-((4-(10,15,20-三苯基-21H,23H-卟啉-5-基)苯基)氨基)丁酸的溶解性质。
Porphyrin and its derivatives is one of the research focuses because of its special physical and chemical properties. The solubility of porphyrin and its derivatives would increase after one hydrophlic group for example carboxylic group were introduced. In this paper, mono amino tetraphenylporphyrin was modified by succinic anhydride so that one carboxylic group was introduced into the target porphyrin mole- cule. The product was characterized by H NMR, IR, and UV - VIS which was first published. The result of element analysis was in the line with calculation. Moreover, the solubility of 4- oxo -4- ((4 - (10, 15,20 - triphenyl - 21H,23H - perphin - 5 - yl) phenyl) amino) botanic acid was reported.
出处
《河北工程大学学报(自然科学版)》
CAS
2010年第2期101-103,共3页
Journal of Hebei University of Engineering:Natural Science Edition
基金
河北省自然科学基金项目(B2008000709)的资助
关键词
单氨基苯基卟啉
琥珀酸酐
mono amine tetraphenylporphyrin
succinic anhydride