鱼腥草不同部位提取物的抗菌抗病毒作用比较

Research of anti-biotic and anti-virus activities on extraction from different parts of Houttuynia cordata

采用水蒸气蒸馏法提取新鲜野生鱼腥草不同部位的挥发油,运用琼脂扩散法分析检测鱼腥草挥发油的抗菌作用,并用微量血凝试验测定了鱼腥草不同部位的挥发油对流感病毒增殖的抑制作用。结果显示:鱼腥草全株均有一定的抑菌作用,其中地下茎提取液对金黄色葡萄球菌、大肠杆菌、酵母菌的抑制作用最强,叶的提取液对痢疾杆菌的抑制作用最强。鱼腥草不同部位的挥发油对流感病毒均有抑制作用,其中叶的提取液在药物质量浓度达31.25 mg/ml时即能抑制病毒的增殖。

WANG Jian, SHI Yu, ZHANG Yong-ze, LI Qing-mei, MEN Jin-e （ 1. Educational Adminrstration, Hebei University of Engineering, Hebei handan 056038, China; 2 Affiliated Hospital, Hebei University of Engineering, Hebei handan 056038, China; 3. First Hospital of Yongnian, Hebei Handan 056000, China） Abstract： The volatile oil was extracted by steam distillation from different part of the fresh wild Houttuyrda cordata. The antibacterial activity of the volatile oil was tested by agar diffusion assay, and the inhibitory effect on the proliferation of influenza vires was analyzed by blood coagulation test. The result shows that the whole plant of H. cordata has an antibacterial effect, and the extract from underground stem has the strongest inhibition on Staphylococlus aureus , Escheichia coli and Saccarom ycescerevisiae ; the extract from leaves has the strongest inhibition on Shigella dysenteroae. The volatile oil from different part of the H. cordata has an inhibitory effect on the influenza virus.