脑梗死与颈椎病变的相关性

CORRELATION OF CEREBRAL INFARCTION WITH CERVICAL VERTEBRAL LESIONS

目的探讨脑梗死与颈椎病变的相关性,为预防脑梗死事件的发生提供临床参考依据。方法采用病例对照研究方法,以年龄和性别为匹配条件,选择住院患者中有脑梗死病史和无脑梗死病史的患者各32例,分别检测血压、血糖、血脂、纤维蛋白原、心电图,检查颈椎相关指标,并将颈椎病患者分型诊断,先进行单因素比较,然后进行Logistic多元回归分析。结果单因素分析结果显示,脑梗死组中高血压、颈椎病(包括混合型颈椎病)、颈椎间盘突出、颈动脉硬化患者明显多于无脑梗死病史组(P<0.05)。Logistic多元回归分析表明,高血压、混合型颈椎病、颈椎间盘突出、颈动脉硬化与脑梗死的发病成正相关,其中颈椎间盘突出是脑梗死事件的最危险因素。结论高血压、混合型颈椎病、颈椎间盘突出、颈动脉硬化是脑梗死的危险因素,其中颈椎间盘突出在脑梗死的发生与发展中起重要作用。

Objective To investigate the correlation of cerebral infarction with cervical vertebral lesions,so as to provide the basis for prevention of this disease.Methods Case-control study was adopted in the investigation.Thirty-two patients with cerebral infarction and 32 without cerebral infarction were investigated.Blood pressure,blood glucose,blood lipid,fibrinogen（FIB）,ECG,and cervical vertebra were examined.Single variable analysis and multiple logistic regression analysis were conducted.Results Single variable analysis showed that the number of patients accompanied with hypertension,cervical spondylopathy（including cervical spondylopathy of mixed type）,cervical intervertebral disk prolapse,or carotid artery atherosclerosis in cerebral infarction group was more than that in control group（P〈0.05）.Multiple logistic regression analysis showed that hypertension,cervical spondylopathy of mixed type,cervical intervertebral disk prolapse,and carotid artery atherosclerosis were positively correlated with cerebral infarction.And the most important risk factor was cervical intervertebral disk prolapse.Conclusion The main risk factors of cerebral infarction are hypertension,cervical spondylopathy of mixed type,cervical intervertebral disk prolapse,and carotid artery atherosclerosis.And cervical intervertebral disk prolapse may play a crucial role in the development of cerebral infarction.