急性冠脉综合征患者介入治疗围术期血瘀证变化的研究

Effect of Interventional Therapy on Blood-stasis Syndrome of Acute Coronary Syndrome Patients in Peri-operation Period

目的:观察急性冠脉综合征(ACS)患者介入治疗围术期血瘀证的变化情况,为急性冠脉综合征血瘀证的研究提供临床依据。方法:采用前瞻性研究,收集急性冠脉综合征患者围术期中医证候资料,并对血瘀证进行评分,采用描述性分析等。结果:介入治疗术后血瘀证评分较术前降低,有51.5%血瘀证评分为重度的患者在术后转为轻度(P<0.05)。当介入治疗后血瘀证合并其他证型时,血瘀分级为重度所占比例最大的是痰浊证,其次为阳虚证。结论:经过介入治疗后大部分急性冠脉综合征患者血瘀证严重程度较治疗前减轻。当血瘀证合并其他证型时,血瘀证严重程度较单纯血瘀证为重。

Objective:To observe the changes of blood-stasis syndrome of acute coronary syndrome(ACS) patients during peri-operation interventional treatment,thus to supply evidence for the treatment of ACS with blood stasis.Methods:A perspective study was carried out in ACS patients during the peri-operation period.The information of traditional Chinese medical syndromes were collected and the score of blood stasis was evaluated with descriptive analysis and rank sum test.Results:The score of blood stasis was decreased after interventional treatment,and 51.5% of the ACS patients with severe blood-stasis syndrome were improved to be mild(P < 0.05).The score of ACS blood-stasis patients complicated with other syndrome patterns was higher than that of the ACS patients with blood stasis alone.ACS blood-stasis patients complicated with yang-deficiency syndrome had the highest blood-stasis score,and phlegm-turbidity syndrome came next.Conclusion:The blood-stasis syndrome in most of the peri-operation ACS patients is relieved after interventional treatment.The blood-stasis syndrome in ACS patients complicated with other syndrome patterns is severer than that in ACS patients with blood stasis alone.