摘要
目的研究愈肝灵胶囊制备与质量控制的方法。方法采用薄层色谱法对愈肝灵胶囊中的博落回进行定性鉴别;以HPLC对制剂中的白屈菜红碱进行含量测定。结果薄层色谱清晰,无干扰,重复性良好;白屈菜红碱在0.1048～0.6289μg.mL-1内呈良好的线性关系,回收率达到99.50%,RSD=1.45%。结论该方法准确度高,重复性好,简便快捷,可作为愈肝灵胶囊的质量控制指标。
OBJECTIVE To study the formulation and preparation procedure of Yuganling capsule and develop an HPLC method for the content determination.METHODS Plumepoppy was identified by TLC,and chelerythrine was determined by HPLC.RESLUTS TLC spots developed were fairly clear,and the blank test showed no interference.Chelerythrine showed a good linear relationship in the range of 0.1048-0.6289 μg·mL^-1 and the average recovery was up to 99.50%,RSD was 1.45%.CONCLUSION The method is accurate,reproducible,simple,and can be used as the quality control of this preparation.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2010年第6期510-512,共3页
Chinese Journal of Modern Applied Pharmacy
关键词
愈肝灵胶囊
制备
质量控制
Yuganling capsule
preparation
quality control
