DNA芯片技术在动物医学中的应用研究进展

Research Progress on Application of DNA Chip in Animal Medicine

随着基因组数据的增长,DNA芯片(DNA Chip)技术得到广泛应用。其集成化、微型化、自动化的优点,为生物、医学、化学等领域的研究提供了一个强有力的工具,笔者从基因表达谱研究、病原微生物检测、细菌分型、基因突变和多态性检测、病原微生物基因组学研究多个方面概述了DNA芯片技术在动物医学中的应用进展、并对DNA芯片技术的原理和分类进行综述。

With the increase of genome ’s numbers,DNA Chip technology gained widely application.Its merit of integration,miniaturization,and automation advantages supply a powerful tool in the field of biology,medicine,chemistry and other research.This article overview DNA chip technology from gene expression spectrum research,identification of pathogenic microbial detection,bacterial typing,genetic mutations and polymorphism detection,pathogenic microbial genomics research in animal medicine application progress,and the principle of DNA chip technology are reviewed.