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两种途径联合注射替罗非班在急性心肌梗死急诊介入治疗中的应用

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摘要 目的:观察两种途径联合注射国产替罗非班(欣维宁)在ST段抬高心肌梗死(STEMI)急诊冠状动脉介入治疗(PCI)中的疗效和安全性。方法:25例STEMI患者行急诊PCI,入导管室后立即静脉注射欣维宁10μg.kg-1,继以0.15μg.kg-1.min-1维持36~48 h,如术中发生无复流/慢血流和急性血栓形成,再冠脉内注射欣维宁10μg.kg-1。观察临床效果及并发症。结果:25例急诊PCI均成功;术中发生慢血流3例,急性血栓形成1例,均经冠脉内注射欣维宁后恢复TIMI 3级血流,血栓消失,无严重并发症和出血事件发生。结论:静脉与冠脉内联合注射替罗非班,是防治STEMI患者急诊PCI术中无复流/慢血流和急性血栓形成的有效方法,不增加出血事件的发生。
出处 《现代医药卫生》 2010年第14期2138-2140,共3页 Journal of Modern Medicine & Health
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参考文献10

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