特发性右心室流出道室性心动过速／室性早搏的性别、年龄和临床特点

The gender, age and clinical feature of idiopathic right ventricular outflow tract ventricular tachycardia/ premature ventricular complexes

目的特发性右心室流出道室性心动过速（室速）／室性早搏（室早）是指不伴有明显器质性心脏病的起源于右心室流出道的室速／室早。对478例特发性右心室流出道室速／室早患者进行系统的回顾性分析，探讨其性别、年龄和临床特点。方法478例患者，平均年龄（39．8±13．8）岁，在过去的15年里，先后因特发性室速／室早在我院住院治疗，并都接受了心内电生理检查和射频消融术治疗。这478例患者室速／室早的射频消融靶点均位于右心室流出道。结果在478例患者中，女性288例（60．3％），男性190例（39．7％），女性／男性比为1．52。出现症状的年龄女性为（41．2±12．7）岁，男性为（37．6±15．0）岁（P〈0．05），所有患者均有不同程度的心悸症状，478例患者中，67例（14．2％）曾出现过黑噱症状，13例（2．7％）曾经出现晕厥。263例（55％）患者在接受射频消融术前，接受过抗心律失常的药物治疗，药物治疗不成功。结论特发性右心室流出道室速／室早患者女性较男性多，女性出现临床症状的平均年龄较男性大，对于这一现象的研究有助于揭示这种心律失常的发生机制。所有患者均有不同程度的心慌症状，有的患者甚至出现黑噱、晕厥。因此对于特发性右心室流出道室速／室早应当更加积极地治疗。

Objective The aim of this study was to clarify gender,age and clinical feature of idiopathic right ventricular outflow tract ventricular taehycardia/premature ventricular complexes （ROVT/PVC）. Methods We studied 478 patients mean age （39. 8 ＋ 13.8 ）years with idiopathic ROVT/PVC who were admitted to our center consecutively in past 15 years. All of them underwent catheter mapping and radiofrequency cathe- ter ablation （RFCA）, and the original sites of ventricular taehycardia/premature ventricular complexes were confirmed by catheter mapping and radiofrequency catheter ablation. Results Of 478 patients, 288 patients （60. 3% ）were female,190 patients（39. 7% ）were male,female/male ratio was 1.52. The early onset of symptom was at （41.2＋ 12. 7 ）years for female, and （37. 6 ＋ 15.0 ）years for male （P 〈 0. 05 ）. Almost all patients had palpitation in varying degrees. Sixty-seven of 478 patients（ 14. 2% ）had history of near-syncope, and 13 of 478 patients（2. 7% ）had history of syncope. Two hundred and sixty-three patients（55% ）underwent unsuccessful treatment with antiarrhythmie drugs before the radiofrequency ablation. Of them, 110 patients （23%）had received one kind of antiarrhythmic drug, 104 patients（ 21.8% ）had received two types of antiarrhythmie drugs, 49 patients （ 10. 3 % ） had received three types of antiarrhythmic drugs. Conclusion ROVT/VPC occur more in female than in male, the early onset of symptom is older for female than for male. Almost all patients have symptom in varying degrees, some of them have near-syncope or syncope.