平阳霉素局部注射联合Nd:YAG激光治疗阴茎头海绵状血管畸形

Study of local injection of bleomycin plus Nd:YAG laser in treatment of veins malformation angioma of the glans penis

目的探讨阴茎头血管畸形的治疗方法。方法本组病例共8例,年龄1 8～25岁,阴茎头直径为1.5～2.0cm不等的蓝紫色蚯蚓状囊性新生物,突出皮肤约0.5～0.8cm。治疗方法:平阳霉素2.0mg+生理盐水适量(视瘤体大小而定),瘤内注射,一个月一次,平均注射3次。注射至瘤体变平后,用长脉宽Nd:YAG激光,能量85～98J/cm^2,脉宽2～12ms,光斑直径6mm,9mm,平均激光治疗次数2.5次。结果 6例治愈,2例显效。结论平阳霉素局部注射联合激光治疗阴茎头血管畸形不会形成阴茎头局部形态改变,无瘢痕及色素改变,疗效确切。

Objective To explore the clinical effect of laser combined with bleomycin （pingyangmycin） on treating angioma of the glans penis. Methods Suspension containing bleomycin and saline was injected once every month into angioma body for three times. The dosage of bleomycin was 2 mg every injection. Based on the differed size of the tumors, different dosages of bleomycin were evenly injected into the remaining tumor tissues until the tissues were a little swelling.Then using Nd：YAG laser to irradiate angioma of the glans penis by the way of non contact scanning until the tissues changed pale and shrank.The diameter of therapy spot was 6-9mm, pulse duration was 2-12ms,and energy density was 85-98J/cm^2.The average therapy times were 2.5. Results Of the 8 cases in the present study, all cases were cured after once of therapy. The incidence of the main complications such as scarring and pigmental change did not occurred. Conclusion Nd： YAG laser combined with bleomycin is a precise, easy, convenient and safe operation to treat angioma of the glans penis with high healing rate and low incidence of complications.