藏药炮制品“佐太”的质量标准研究

Quality Control of Traditional Tibetan Medicine Zsuotai

目的:建立藏药炮制品"佐太"的质量标准。方法:收集青海、西藏、四川、甘肃四省区的佐太样品,采用化学鉴别法进行佐太的汞盐鉴别;采用硫氰酸盐容量法测定佐太中硫化汞的含量。结果:硫氰酸盐容量法对藏药"佐太"中的硫化汞(HgS)含量测定,重现性好(RSD=0.68%),硫化汞(HgS)在0.0006～0.2128g线性关系良好(r=0.9999),平均回收率(n=6)为100.94%,RSD=0.66%,佐太中硫化汞(HgS)的平均含量为54.50%。结论:用硫氰酸盐容量法测定佐太中的硫化汞(HgS)含量方法简单,准确,重复性好;各地佐太样品中的硫化汞(HgS)的含量差别不大。

Objective：To establish the method of quality control for traditional Tibetan Medicine Zsuotai.Methods：Collecting the samples of Tsuotai from Qinghai,Tibet,Sichuan,and Gansu province,to detect Hg2＋ by Zsuotai reacted with HCl-HNO3（3∶1）,and to determine the quantity of HgS in Zsuotai by sulfocyanate volumetric method.Results：The method for the determination of HgS in Zsuotai was in good reproducibility（RSD=0.68%）.The calibration curve was linear（r= 0.9999）within-0.0002～0.2123 g of mercuric sulfide.The recovery was 100.94%（RSD=0.66%）.Conclusions：This method is convenient and accurate,so it can be used to establish quality control of the medicinal material.