酒石酸唑吡坦片致精神错乱

Mental disorder secondary to zolpidem tartrate

1例74岁男性患者,因胃癌化疗住院。次日晚因入睡困难给予酒石酸唑吡坦10mg口服。用药1h后患者出现烦躁,意识模糊,幻听,谵妄。肌内注射异丙嗪、氟哌啶醇对症处理,症状无改善。4h后患者症状自行消失,神志恢复,但不能回忆起之前发生的事情。停用此药,上述症状未再发生。

A 74-year-old man with gastric cancer was hospitalised for chemotherapy. The next day,he was given zolpidem tartrate 10 mg for insomnia at night. One hour later,he developed agitation,confusion,auditory hallucinations,and delirium. These symptoms did not relieved after administration of promethazine and haloperidol. Four hours later,his symptoms subsided sponancously and his consciouness recovered,however,he could not remember the prior events. The above-mentioned symptoms did not reccur after the drug discontinuation.