经颅多普勒超声动态评价立普妥对脑梗死患者脑血流动力学的影响

Evaluation of effects of lipitor on cerebral hemodynamics of ischemic stroke patients with transcranial Doppler

目的通过经颅多普勒超声动态评价立普妥对脑梗死患者脑血流动力学的影响。方法通过经颅多普勒超声检查100例首次急性脑梗死住院患者的脑血流动力学,根据是否规律服用立普妥分为:服药组53例和未服药组47例。发病3个月后再次随访经颅多普勒超声。结果与发病1周内比较,服药组患者发病3个月后大脑中动脉血流速度明显增快,搏动指数明显下降(P<0.05);未服药组患者发病3个月后双侧大脑中动脉血流速度和搏动指数差异无统计学意义(P>0.05)。结论立普妥对改善脑梗死脑血流动力学有一定作用。

Objective To evaluate the effects of lipitor on the cerebral hemodynamies of ischemic stroke patients with transcranial Doppler（TCD）. Methods 100 inpatients with acute ischemic stroke were divided into two groups according to whether they took lipitor after stroke. The change of the cerebral hemodynamics in two groups was examined by TCD three months after stroke. Results The blood velocity in lipitor group significantly increased compared with that in control group （P 〈 0.05）. The pulse index in lipitor group significantly decreased compared with that in control group （P 〈 0.05）. Conclusions Lipitot may have effects on improving the cerebral hemodynamics of patients with ischemie stroke.