期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

诱导细胞死亡DNA片段化因子a样效应因子A基因对肥胖和代谢综合征作用的研究进展 被引量：3

下载PDF
导出
摘要 近年研究发现，诱导细胞死亡DNA片断化因子α样效应因子（celldeath—inducing DNA fragmentation factor alphalikeeffeetor，CIDE）A可通过调节线粒体解偶联蛋白1（UCP1）活性来调节小鼠脂肪和葡萄糖代谢。
作者 张玲 戴颖 王玮 王嵬 华琦
机构地区 首都医科大学公共卫生与家庭医学学院流行病与卫生统计学系 大学宣武医院心脏中心
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2010年第7期658-660,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金 国家自然科学基金(30800949) 北京市自然科学基金(7072032) 北京市优秀人才培养资助个人项目(20081D0501800213) 首都医科大学基础临床合作基金(09JL15)
关键词 细胞凋亡 DNA 肥胖症 高血糖症 线粒体
分类号 R589 [医药卫生—内分泌]
  • 相关文献

参考文献22

  • 1Zhou Z,Yon Toh S, Chen Z, et al. Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat Genet,2003, 35:49-56.
  • 2Nordstrom EA, Ryden M, Backlund ECZZ, et al. A human- specific role of cell death-inducing DFFA(DNA fragmentation factor-alpha)-like effector A(CIDEA) in adipocyte lipolysis and obesity. Diabetes,2005,54 : 1726-1734.
  • 3Dahlman I,Kaaman M,Jiao H,et al. The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects. Diabetes, 2005,54 : 3032-3034.
  • 4Zhang L, Miyaki K, Nakayama T, et al. Cell death-inducing DNA fragmentation factor alpha-like effector A (CIDEA) gene VllSF(G→T) polymorphism is associated with phenotypes of metabolic syndrome in Japanese men. Metabolism, 2008,57 : 502-505.
  • 5Inohara N, Koseki T, Chen S, et al. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. EMBO J, 1998, 17: 2526- 2533.
  • 6Viswakarma N,Yu S,Naik S,et al. Transcriptional regulation of Cidea, mitochondrial cell death-inducing DNA fragmentation factor alpha-like effector A in mouse liver by peroxisome proliferator-activated receptor alpha and gamma. J Biol Chem, 2007,282 : 18613-18624.
  • 7Hallberg M, Morganstein DL, Kiskinis E, et al. A functional interaction between RIP140 and PGC lalpha regulates the expression of the lipid droplet protein CIDEA. Mol Cell Biol, 2008,28 : 6785-6795.
  • 8Christian M, Kiskinis E, Debevec D, et al. RIP14 0-target ed repression of gene expression in adipoeytes. Mol Cell Biol, 2005, 25 :9383-9391.
  • 9Pettersson AT, Laurencikiene J, NordstrOm EA, et al. Characterization of the human CIDEA promoter in fat cells. Int J Obes(Lond), 2008,32 : 1380-1387.
  • 10Iwahana H, Yakymovych I, Dubrovska A, et al. Glycoproteome profiling of transforming growth factor-beta(TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbetal-dependent apoptosis. Proteomics, 2006,6:6168-6180.

同被引文献24

  • 1龚大为,李平,朱大龙.脂肪细胞因子研究进展[J].中国糖尿病杂志,2007,15(10):637-638. 被引量：7
  • 2Mary HPA, Susheela GK, Jayasree S, et al. Phytochemi- cal characterization and antimicrobial activity of Curcuma xanthorrhiza Roxb E J ]. Asian Pacific Journal of Tropical Biomedicine, 2012, 2(2): $637-$640.
  • 3Aggarwal BB, Yuan W, Li S, et al. Curcumin-free tur- meric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric ~ J ]. Mol Nutr Food Res, 2013, 57 : 1529-1542.
  • 4Su JY, Tan LR, Lai P, et al. Experimental study on anti- inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of chrysanthemum indicum, patchouli oil and zedoary turmeric oil in vivo ~ J ]. J Eth- nopharmacol, 2012, 141(2): 608-614.
  • 5Cheng SB, Wu LC, Hsieh YC, et al. Supercritical car- bon dioxide extraction of aromatic turmerone from Curcu- ma longa Linn. induces apoptosis through reactive oxygen species-triggered intrinsic and extrinsic pathways in human hepatocellular carcinoma HepG2 cells ~ J 1. J Agric Food Chem, 2012, 60(38): 9620-9630.
  • 6Singh G, Kapoor IP, Singh P, et al. Comparative study of chemical composition and antioxidant activity of fresh and dry rhizomes of turmeric ( Curcuma longa Linn) E J]. Food Chem Toxicol, 2010, 48 (4) : 1026-1031.
  • 7Bordelon H, Russ PK, Wright DW, et al. A magnetic bead-based method for concentrating DNA from human urine for downstream detection~ J]. PLoS One, 2013, 8 (7) : 058369. doi: 10. 1371/journal. pone. 0068369. Print 2013.
  • 8Hong JM, Park CS, Nam-Goong IS, et al. Curcumin enhances docetaxel-induced apoptosis of 8505C anaplas- tic thyroid carcinoma cells E J ]. Endocrinol Metab, 2014, 29( 1 ) : 54-61.
  • 9Shao SL, Sui W J, Li S, et al. Effects of proliferation and apoptosis in human gastric cancer cell line SGC- 7901 induced by zedoary turmeric oil ~ J ]. Advanced Materials Research, 2012, 59(9) : 67-70.
  • 10王莉,尹芳,杜昱蕾,杜文琪,陈蓓,张永国,陈铮,乔泰东,樊代明.ATM在人胃癌细胞系的表达及其在细胞DNA损伤中的作用[J].现代肿瘤医学,2010,18(3):433-436. 被引量：5

引证文献3

二级引证文献18

中华老年心脑血管病杂志
2010年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部