灰阶超声在评价肝癌微波消融范围的可行性研究

Evaluation of coagulated area after microwave ablation of liver carcinomas by gray-scale ultrasound

目的评价灰阶超声在肝癌微波消融治疗时对凝固范围的预测价值。方法本组研究共41例患者41个肝癌病灶,每个病灶微波消融治疗结束后,记录灰阶超声显示由气泡形成的强回声范围的横径,以及治疗后1h超声造影显示实际坏死范围的横径,将两者进行比较。结果微波治疗时灰阶超声显示的强回声横径为(33.3±5.5)mm;微波消融治疗后超声造影显示所有病灶均完全消融,坏死区域横径为(23.5±4.6)mm。两者比较具有较好的正相关性(r=0.86,P<0.01)。结论微波消融时利用灰阶超声初步评判肝癌实际坏死的范围,对微波消融治疗肝癌的疗效判断具有较好的实用价值。

Objective To investigate the value of gray-scale uhrasonography in predicting the coagulated area of ablation in microwave therapy of liver carcinomas. Methods The spread of microbubbles during microwove ablation was observed by gay-scale ultrasonography in 41 patients with 41 liver carcinomas and the largest minor axis of the lesions were compared with those of the defect of enhancement by contrast-enhanced ultrasonography （CEUS）. Results The minor axis [ （33.3 ± 5.48） mm ] of the area of hyperechogenicity after ablation observed by gray-scale uhrasonography was significantly correlated with that [ （23.5 ± 4.59）mm] of the defect enhancement observed by CEUS（ r = 0. 86,P 〈 0.01 ）. CEUS showed that all lesions were completely ablated. Conclusion The CEUS is helpful in predicting therapeutic efficacy of microwave ablation in liver carcinomas by observing the hyperechogenic area of microbubbles during the procedure.