通络脉合剂治疗血栓闭塞性脉管炎临床研究

Clinical study on treating Thromboangiitis obliterans with Tongluomai Heji

目的:观察通络脉合剂治疗血栓闭塞性脉管炎热毒伤阴证的疗效。方法:采用随机、对照研究的方法,将60例血栓闭塞性脉管炎属热毒伤阴证患者分为2组治疗。治疗组30例,常规应用扩张血管药物加口服通络脉合剂;对照组30例,常规应用扩张血管药物加口服通塞脉片。结果:治疗组在临床疗效、经皮氧分压及部分症状积分的改善方面均优于对照组,两组比较有显著性差异(P<0.05)。两组间踝/肱比较无统计学意义。结论:采用通络脉合剂为主的治疗方法效果优于通塞脉片治疗方法。通络脉合剂是治疗血栓闭塞性脉管炎热毒伤阴证安全、有效的药物。

Objective：To observe the effect of Tongluomai Heji on Thromboangiitis obliterans with syndrome of yin injured by heat toxicity.Methods：60 subjects who suffered from Thromboangiitis obliterans with syndrome of yin injured by heat toxicity were divided into two groups：treatment group （30 cases）,given common vascular dilatation drugs and Tongluomai Heji;control group （30 cases）,given common vascular dilatation drugs and Tongsaimai Pills.Results：In the clinical efficacy,transcutaneous oxygen pressure and the improvement of the symptom score,the treatment group was better than the control group （P0.05）.Between the two groups,ankle/brachial ratio had no statistical significance.Conclusion：The treatment group was more effective than control group.Tongluomai Heji was safe and effective in treating Thromboangiitis obliterans with syndrome of yin injured by heat toxicity.