期刊文献+

宫颈病变中HPV DNA的物理状态和病毒载量的研究进展 被引量:6

下载PDF
导出
摘要 宫颈癌是全球危及女性生命的第二高发肿瘤。多因素协同作用促使疾病发生发展,其中人乳头瘤病毒(HPV)感染是导致宫颈癌及癌前病变的必要条件。现就HPV病毒DNA整合状态、整合位点、病毒载量等因素与宫颈癌发生关系的近期研究进展作一综述。
作者 孙伟 肖长义
机构地区 三峡大学医学院
出处 《现代妇产科进展》 CSCD 北大核心 2010年第6期461-464,共4页 Progress in Obstetrics and Gynecology
基金 国家自然科学基金项目(No:30770104) 湖北省教育厅重大课题[鄂教科No:(2007)4号Z200713002]资助
  • 相关文献

参考文献17

  • 1Parkin M, Bray F. Chapter 2:the burden of HPV-related cancers [ J ]. Vaccine, 2006,24 : 3,11-25.
  • 2Song SH, Lee JK, Oh M J, et al. Risk factors for the progression or persistence of untreated mildisplasia of uterine cervix[ J ]. Int J Gynecol Cancer,2006,16 : 1608-1613.
  • 3Vinokurova S,Wentzensen N, Kraus I,et al. Type-dependent integration frequency of human papillomavirus genomes in cervical lesions [ J ]. Cancer Res, 2008,68 : 307- 313.
  • 4Pett M, Coleman N. Integration of high-risk human papillomavirus:a key event in cervical carcinogenesis? [ J]. J Pathol, 2007,212 : 356 -367.
  • 5Cricca M, Morselli-Labate AM, Venturoli S, et al. Viral DNA load, physical status and E2/E6 ratio as markers to grade HPV16 positive women for high-grade cervical lesions [ J ]. Gynecol Oncol, 2007,106:549-557.
  • 6Kulmala SM,Syrjanen SM, Gyllensten UB, et al. Early integration of high copy HPV16 detectable in women with normal and low grade cervical cytology and histology[ J]. J Clin Pathol,2006,59:513-517.
  • 7Hernadi Z, Sapy T, Krasznai ZT. The prevalence of the HPV 16 genome ,integrated viral status and p53 genotype in cervical cancer population of north-eastern Hungary, the correlation with the established markers of tumour progression[ J ]. Eur J of Obstet & Gynecol and Reprod Biol,2004,113:83-86.
  • 8Khouadri S, Villa LL, Gagnon S, et al. Viral load of episoreal and integrated forms of human papillomavirus type 33 in high-grade squamous intraepithelial lesions of the uterine cervix[ J ]. Int J Cancer,2007,121:2674-2681.
  • 9Coutlee F, Trottier H, Gagnon S, et al. Low-risk human papillomavirus type 6 DNA load and integration in cervical samples from women with squamous intraepithelial lesions [ J ]. J Clin Virol, 2009,45 : 96-99.
  • 10Longworth MS, Laimins LA. Pathogenesis of human papillomaviruses indifferentiating epithelia [ J ]. Microbiol Mol Biol Rev, 2004,68 : 362-372.

同被引文献53

引证文献6

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部