粉底对轻中度痤疮治疗效果的影响

The interference of foundation on the efficacy of anti-mild-to-moderate acne treatment

目的:研究不含抗痤疮成分的粉状粉底对轻中度痤疮疗效的影响。方法:根据痤疮整体严重度的评分标准,65名符合轻中度痤疮标准的18～35岁健康女性作为本研究的受试者,随机分为试验组和对照组。试验组在使用粉底的同时接受过氧化苯甲酰凝胶治疗,而对照组只接受过氧化苯甲酰凝胶治疗。临床评估、拍照及受试者自我问卷评估分别在试验开始前、试验开始后第3天、1周、2周和4周时进行。结果:经过4周试验后,2组受试者的痤疮严重程度得到改善。无论是试验开始前还是试验结束时,痤疮的严重程度两组间均未见明显差异。两组受试者自我评估均为痤疮的严重程度得到改善。结论:轻中度痤疮患者在接受抗痤疮治疗的同时使用粉底并不影响其疗效,而且有益于提高患者的自信。

Objective： To investigate the impact of one classical powder foundation on the efficacy of anti-mild-to-moderate acne treatment. Methods：A total of 65 Chinese females with mild to moderate facial acne, aged between 18-35 years old, were randomized to allocate into test and control groups for 4 week study. The test group received benzoyl peroxide gel to anti-acne, meanwhile applied to the foundation 3 times per week at least; the control group only received benzoyl peroxide gel. Clinical evaluation of safety and efficacy, photographs and subject＇s self-assessment questionnaire were taken at baseline, 3 days, 1, 2 and 4 weeks. Results：After 4 weeks, the severities of ache were decreased for both two groups. There was no significant difference between two groups about clinical efficacy grading before and at the end of the study. After 4 week study, the subjects of both groups were self-perceived the number of their facial acne was decreased. Conclusions：There is no negative interference of the foundation on the efficacy of anti-mild-to-moderate ache treatment from clinical grading, and test powder foundation can improve the confidence of acne sufferers.