乌鲁木齐地区淋球菌、沙眼衣原体、溶脲脲原体感染情况调查

Detection and analysis of Neisseria gonorrhoeae,Chlamydia trachomatis and Ureaplasma urealyticum infection in patients with urogenital tract infections in Urumqi,China

目的分析新疆乌鲁木齐地区淋球菌(Neisseria gonorrhoeae,NG)、溶脲脲原体(Ureaplasma urealyticum,UU)和沙眼衣原体(Chlamydiatrachomatis,CT)的感染情况。方法运用荧光定量PCR对乌鲁木齐地区316例疑似淋菌性/或非淋菌性尿道炎患者NG、CT和UU感染情况进行检测。结果 316例受检者NG感染率为21.2%,CT感染率为16.5%,UU感染率为24.7%,NG、CT、UU合计感染率为62.3%。男女、汉族和维吾尔族患者民族间NG、UU和CT感染率差异无统计学意义(P>0.05)。结论乌鲁木齐地区泌尿生殖道感染门诊患者中NG、CT和UU感染率较高;在检测NG、CT和UU方面,荧光定量PCR简便、快速,敏感性高、特异性强。

Objective To detect and analyze urogenital tract infections of Neisseria gonorrhoeae（NG）,Chlamydia trachomatis（CT） and Ureaplasma urealyticum（UU） in Urumqi.Methods Three hundred and sixteen specimens from patients with a urogenital tract infection were tested for NG,CT,and UU using fluorescent quantitative PCR（FQ-PCR）.Results The overall rate of infection was 62.3%;the rate of infection with NG,CT,and UU was 21.2%（67/316）,16.5%（52/316）,and 24.7%（78/316）,respectively.There were no significant differences in the rate of NG,CT,and UU infection among the genders and the Uygur and Han ethnic groups.Conclusion Patients with urogenital tract infections in Urumqi had a high rate of infection with NG,CT,and UU.The FQ-PCR assay is easy to perform,quick,and able to detect NG,CT,and UU in urogenital tract infections with a high level of sensitivity and specificity.