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Th17细胞与Ⅰ型变态反应性疾病

Th17 cell and Type Ⅰ allergic disorders
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摘要 Th17细胞是近年来发现的一种新的CD4＋T细胞亚型.该细胞能产生以IL-17为主的多种细胞因子,参与炎症反应,与自身免疫性疾病、感染性疾病和变态反应性疾病等的发病关系密切.本文综述Th17细胞及其产生的细胞因子在Ⅰ型变态反应性疾病中的作用及研究进展. Th17 cells are discovered in recent years as a new class of CD4＋ T cell subsets. It can produce mainly IL-17A （IL-17） and some other cytokines which play an important role in inflammation and have a close relationship with the pathogenesis of autoimmune,infectious and allergic disorders. This review will summarize the roles and the progress in research of Th17 cells and its cytokines in type Ⅰ allergic disorders.
作者 陈鹏远 朱可建
机构地区 浙江大学医学院附属邵逸夫医院皮肤科
出处 《国际呼吸杂志》 2010年第13期827-830,共4页 International Journal of Respiration
关键词 TH17细胞 Ⅰ型变态反应性疾病 白介素17 Th17 cell Type Ⅰ allergic disorders Interleukin-17
分类号 R593.1 [医药卫生—内科学]
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参考文献28

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国际呼吸杂志
2010年 第13期

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