摘要
目的研究丹龙胶囊抗血栓形成的作用。方法手术结扎大鼠下腔静脉使大鼠下腔静脉内形成血栓,称量血栓湿重和干重;用血栓生成仪观察记录电刺激5min内颈总动脉平均阻塞率(%);用血小板聚集凝血因子分析仪测定受试药对二磷酸二腺苷(ADP)诱导血小板聚集的抑制作用。结果丹龙胶囊能够减少下腔静脉血栓形成;降低颈总动脉平均阻塞率;抑制由二磷酸二腺苷引起的家兔血小板聚集。结论研究结果证明丹龙胶囊具有抑制血栓形成的作用。
Objective To study the action of DanlongCAPS for inhibiting thrombosis in Methods The inferior vena of the rat was ligated to make thrombosis in inferior vena,then the dry weight and humid weight of the internal clot was calculated; with the equipment of internal clot formation to observe and record the average blockage rate of the arteria carotis communis in 5 minutes of electric stimulation;the inhibiting effect of DanlongCAPS on adenosine diphosphate （ ADP ） induced by platelet aggregation was measured by platelet aggregation meter. Results DanlongCAPS could reduce the internal clot of the inferior vena,decrease the average blockage rate of the arteria carotis communis,and inhibite the platelet aggregation induced by adenosine diphosohate （ ADP） in the rabbit. Conclusion The results of the study confirm that the DanlongCAPS has the effect of inhibiting thrombosis.
出处
《实验动物科学》
2010年第3期19-21,共3页
Laboratory Animal Science
关键词
丹龙胶囊
血栓
血小板聚集
DanlongCAPS
Internal clot
Platelet aggregation
