针刺对手阳明大肠经线下深部组织中氧分压的影响

Observation on Changes of Oxygen Partial Pressure in the Deep Tissues along the Large Intestine Meridian During Acupuncture in Healthy Subjects

目的:探讨与手阳明大肠经线相关组织的能量代谢特点。方法:31名健康志愿者,沿手阳明大肠经脉循行线上取5个测试点,测试深度为皮下1.5cm,其中3个为穴位(臂臑、手五里、手三里),2个为经上非穴位点(曲池-臂臑中点、曲池-阳溪中点);同时在各测试点内外1.5～2cm处各取1个非经对照点,形成5个横向测试水平。观察电针前、电针合谷穴时及电针后各测试点氧分压的变化情况,连续记录60min。结果:正常情况下沿手阳明大肠经循行线上测试点深部组织氧分压非常显著地高于两侧非经对照部位(P<0.01)。电针合谷穴时,手阳明大肠经线上测试点氧分压降低,与电针前比较差异有统计学意义(P<0.05)。电针后手阳明大肠经上氧分压与电针期间比较差异无统计学意义(P>0.05),与电针前比较显著降低(P<0.01,P<0.05)。而两侧非经对照部位,电针时、电针后各测试点的氧分压与电针前比较均无明显变化(P>0.05)。结论:常态下手阳明大肠经循行线下深部组织中的能量代谢较其两侧非经对照部位旺盛,电针可以使沿经组织的氧利用率提高,能量代谢进一步增强。提示经脉可能是与物质、能量和信息的转换和传递相关的某种通道。

Objective To observe changes of the partial oxygen pressure in the deep tissues along the Large Intestine Meridian （LIM） during acupuncture stimulation, so as to reveal the characteristics of energy metabolism in the tissues along the LIM. Methods Thirty-one healthy volunteer subjects were enlisted in the present study. Partial oxygen pressure （POP） in the tissues （at a depth of about 1.5 cm） of acupoints Binao （LI 14）, Shouwuli （LI 13）, Shousanli （LI 10）, 2 non-acupoints Ethe midpoints between Quchi （LI 11） and LI 14, and between Yangxi （LI 5） and LI 11） of the LIM, and 10 non-meridian points, 1.5- 2.0 cm lateral and medial to each of the tested points of the LIM was detected before, during and after electroacupuncture （EA） stimulation of Hegu （LI 4） by using a tissue oxygen tension needle-like sensor. Rcsu｜ts In normal condition, the POP values in the deep tissues along the LIM were significantly higher than those of the non-meridian control points on its bilateral sides. During and after EA of Hegu （LI 4）, the POP levels decreased significantly in the deep tissues along the LIM in comparison with pre-EA （P〈0.01）, and had no apparent changes in the non-meridian control points （P〉0.05）. Conclusion POP is significantly higher in the deep tissues along the LIM of healthy subjects under normal conditions, which can be downregulated by EA of Hegu （LI 4）, suggesting an increase of both the utilization rate of oxygen and energy metabolism after EA.