围手术期抗生素预防性应用的疗效分析

Analysis of antibiotics effect for preventive application

为探讨围手术期抗生素的预防性应用的效果．我们采用术前半小时、术后12小时内各静脉给予抗生素的方法（严重污染或免疫力低下者术后仍给予抗生素数次或数日）．其应用1294例（实验组）．并与传统的给药方法比较（对照组1143例），结果实验组的切口感染率较对照组明显降低（P＜0．05），且住院天数及费用均较对照组明显降低（P＜0．05）。认为围手术期抗生素的预防性应用是安全、有效的。

In order to explore antibiotics effect for preventive application in perioperation period, we used antibiotics at 30 minutes preoperatively and within 12 hours postoperatively by intravenous (trial group 1294 cases). The patients who were contaminated seriously or in hypoimmuntity should be treated by antibiotics for several times or days postoperatively. Comparing with the traditional way of antibiotics application (control group 1143 cases ). we discovered that the incision infection rate and the cost of hospitalization in trial group patients were lower than those in control group patients (P＜0. 05 ). We think that it is safe and effective to use antibiotics in perioperation period.