子痫前期合并颅内静脉窦血栓形成的回顾性研究

Retrospective study on patients of preeclampsia combined with thrombosis of intracranial venous sinus

目的:针对子痫前期颅内静脉窦血栓形成的危险因素及治疗进行回顾性分析。方法:回顾性分析2004～2009年6年间12例子痫前期颅内静脉窦血栓患者治疗的临床资料。结果:1例患者子痫前期合并颅内静脉窦血栓形成发生在产前,11例发生在产后,以头疼、癫痫、视力障碍为主要症状。经治疗后患者临床症状明显改善。结论:子痫前期围产期颅内静脉窦血栓形成与子痫前期所致血液高凝状态和血液滞流有关,病情凶险,及时抗凝、溶栓治疗可改善患者的结局。

Objective：To analyze the risk factors and treatment of thrombosis of intracranial venous sinus in patients with preeclampsia retrospectively.Methods：Clinical data of 12 patients of preeclampsia combined with thrombosis of intracranial venous sinus from 2004 to 2009 were analyzed retrospectively.Results：One patient occurred before delivery, 11 patients occurred after delivery, the main symptoms were headache, epilepsy and visual disturbance; after treatment, the clinical symptoms recovered significantly.Conclusion：Thrombosis of intracranial venous sinus in patients with preeclampsia during perinatal period is related to high blood coagulation state and blood stagnation induced by preeclampsia,the disease is dreadful, timely anticoagulation and thrombolysis may improve the outcomes of patients.