乙型肝炎肝硬化毒瘀虚相关病机与论治探讨

Approach of Pathogenesis and Determination of Treatment on Hepatic Cirrhosis from Serum Hepatitis belonging to Toxin,Stasis and Consumption

乙型肝炎肝硬化为慢性乙型肝炎肝病发展至晚期的阶段,属中医积聚、鼓胀等病证范畴,病情复杂多变。临床多表现出毒瘀阻络,肝体变硬,正气亏虚等证侯。毒蕴不散,邪瘀成积,积损致虚的病机贯穿肝硬化全程,针对该病不同发展阶段病机特点,应辨证采用解毒、化瘀、补虚方法治疗。毒瘀搏结,邪结肝体,治宜解毒化瘀;瘀毒羁留,肝硬脾积,治宜化瘀消积;毒瘀耗损,正虚不足,治宜扶正补虚;并发坏证,治宜谨守病机。辨证论治有利于控制病情,延缓肝病进展,降低死亡率。

Hepatic cirrhosis the advanced stage. It belonged caused by serum hepatitis resulted from liver disease of chronic serum hepatitis to to cumulated disease or meteorism in traditional Chinese medicine. It is complicated, fickle and variable. The symptoms displayed toxin and stasis blocking collaterals, liver body hardening, and healthy energy weakening. Pathogenesis of collected toxin not disappearing, evil stasis becoming cumulation, and cumulated harm leading to consumptive disease runs through the whole course of hepatic cirrhosis. To aim directly at toxin, stasis and consumption in different stages, differentiation should apply disintoxicating, dissolving stasis, and supplying deficiency. Toxin and stasis tangle and interact, then to gather into liver. So treatment should be according to the methods of detoxificating and dissolving stasis. Because of stasis and toxin stop over, liver hardens and spleen produces sbdominal mass. So the treatment should dissolve stasis to remove stagnation. Because of toxin and stasis damage leading to asthenia of healthy energy, treatment should strengthen body resistance and replenish qi. If some deteriorated syndromes happened, doctors should cautiously grasping pathogenesis So disease can be controlled, disease progression can be delayed and death rate can be cut down.