摘要
目的分析青年妇女宫颈浸润癌的临床特点及预后。方法对1976年7月~1992年7月采用放疗、化疗、手术及冷冻两种以上方法综合治疗的77例青年妇女宫颈浸润癌进行回顾性分析。结果77例患者占同期宫颈癌的3.88%,平均年龄31.9岁。肿瘤直径大于4cm者47例;腺癌29例,占37.66%;组织学分化为Ⅲ级32例,其中腺癌11例,鳞癌21例。ⅡB期以上为58例,占75.32%。5年生存率为50.65%。血行转移以腺癌多见,多发生在半年之内,死亡率高。结论青年妇女宫颈癌影响预后的主要因素为临床分期、组织学类型、组织学分化程度及原发肿瘤的大小。
Objective To analyze the clinical characteristics and prognosis of cervical carcinoma of young woman.Methods From July 1976 to July 1992,77 cases of cervical invasive carcinoma of young women diagnosed in our hospital were treated with combined therapy,including radiotherapy,chemotherapy, freezing and surgery resection.Results These young cases occupied 3.88% of all cervical carcinoma in that period. The average age was 31.9 years. The size of tumor large than 4 cm in diameter was 47 cases.The common types were adenocarcinoma and squamous cell carcinoma, occupied 37.66% and 59.74%,respectively. The overall 5-year survival rate was 50.65%. Blood metastasis was common in adenocarcinoma,most of cases were disseminated in half a year after diagnosis and a high mortality were observed in these patients.Conclusion The mainly prognostic factors were clinical stage, histological type and the size of the primary tumor.