肺腺鳞癌的临床特点及疗效分析

Analysis of Therapeutic Effectiveness and Clinical Features for Adenosquamous Carcinoma of the lung.

目的分析肺腺鳞癌的临床特点和疗效。方法１９８７年４月至１９９４年４月５０例肺腺鳞癌采用单纯手术、术后放疗、术后化疗、术后放疗和化疗、放疗加化疗。其疗效采用Ｋａｐｌａｎ－Ｍｅｉｅｒ法计算，Ｌｏｇ－ｒａｎｄ检验。结果肺腺鳞癌患者出现临床症状１月内有３２％为晚期，８０％患者有纵膈或肺门淋巴结肿大，病检癌转移率为７０．６％；本组１、３、５年生存率分别为５８．０％、１６．０％和３．３％。结论肺腺鳞癌具有侵袭力强、早期转移、进展迅速等低分化癌特征。早期诊断，综合治疗是获得长期生存的关键。

Objective To analyze the therapeutic effectiveness and clinical features for adenosquamous carcinoma of the lung. Methods Fifty patients with adenosquamous carcinoma of the lung were treated by different therapy methods from 1987 to 1994. Kaplan-Meier Methods and log-rank test were used to evaluate survival rates. Results Of 80% the mediastinum or hilar lymph nodes enlargement were found in the adenosquamous carcinoma of the lung by clinical methods. There were 190 lymph nodes by operation of 38 patients, of which 134 were found to be metastasis of carcinoma (70.5%). The 1.3 and 5-year's survival rates were 58.0%16.0% and 3.3% respectively. Conclusions This cancer is easy to invade its adjacent organ, spread early. It is a poorly differentiated cancer. We believe that it is door bolt for successfully to find early, diagnose early and treat unitedly.