肥胖与饮酒对男性高尿酸血症的影响

The effect of the obesity and drinking on hyperuricemia in male

目的研究男性高尿酸血症的影响因素。方法分析体检人群中男性血尿酸含量及其相关影响因素。将血尿酸≥420μmol/L的6 056例为高尿酸血症病例组,血尿酸<420μmol/L的10 696例为正常对照组,采用Logistic回归分析评估高尿酸血症风险因素,以及肥胖与饮酒同时存在时对高尿酸血症的影响。结果随着肥胖程度和饮酒量的增加,高尿酸血症患病OR(odds ratio)值明显增加。结论肥胖和饮酒与高尿酸血症有关,二者同时存在时更增添了高尿酸血症患病的风险。

Objective To investigate the effective factors of hyperuricemia in male.Methods Data were collected from male subjects for physical examinations in our hospita1.The cases comprised 6 056 male with hyperuricemia（serum uric acid level ≥420 μmol/L）;the controls were 10 696 men（serum uric acid level less than 〈420 μmol/L）.Logistic regression analysis was used to assess risk factors for hyperuricemia and the interaction between obesity and drinking in hyperuricemia.Results The odds ratio for hyperuricemia significantly increased with increasing of BMI and alcohol intake.Conclusion Our results suggest that obesity and alcohol intake are relate to hyperuricemia,the combining of obesity and drinking more dramatically increase the risk for hyperuricemia.