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Th17细胞与多发性硬化／实验性自身免疫性脑脊髓炎 被引量：3

Th17 cells and multiple sclerosis/experimental autoimmune encephalomyelitis
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摘要 多发性硬化（multiple sclerosis，MS）及其理想动物模型实验性自身免疫性脑脊髓炎（experimental autoimmune encephalomyelitis, EAE）是主要累及中枢神经系统的自身免疫性疾病。
作者 樊红翠 马存根
机构地区 山西大同大学脑科学研究所
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2010年第7期751-753,共3页 Chinese Journal of Neuromedicine
关键词 TH17细胞 多发性硬化 实验性自身免疫性脑脊髓炎
分类号 R744.51 [医药卫生—神经病学与精神病学]
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参考文献22

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  • 2Cua DJ,Sherlock J,Chen Y,et al.Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain[J].Nature 2003,421(6924):744-748.
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  • 7Ogura H,Murakami M,Okuyama Y,et al.Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction[J].Immunity,2008,29(4):628-636.
  • 8Coquet JM,Chakravarti S,Smyth MJ,et al.Cutting edge:IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis[J].J Immunol,2008,180(11):7097-7101.
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同被引文献34

  • 1Miller D, Barkhof F, Montalban X, et al. Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis[J]. Lancet Neurol, 2005, 4 (5): 281-288.
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  • 3Bitsch A, Schuchardt J, Bunkowski S, et al. Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation[J]. Brain, 2000, 123(Pt 6): 1174-1183.
  • 4Kuhlmann T, Lingfeld G, Bitsch A, et al. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time[J]. Brain, 2002, 125(Pt 10): 2202-2212.
  • 5Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria" [J]. Ann Neurol, 2005, 58(6): 840-846.
  • 6Kume A, Isikay IC, Karlioguz K, et at. A clinically isolatedsyndrome: a challenging entity: multiple sclerosis or collagen tissue disorders: clues for differentiation[J]. J Neurol, 2008, 255 (11): 1625-1635.
  • 7Brettschneider J, Maier M, Arda S, et al. Tau protein level in cerebrospinal fluid is increased in patients with early multiple sclerosis[J]. Mult Scler, 2005, 11(3): 261-265.
  • 8Colucci M, Roccatagliata L, Capello E, et al. The 14-3-3 protein in multiple sclerosis: a marker of disease severity [J]. Mult Scler, 2004, 10(5): 477-481.
  • 9Guimaraes I, Cardoso MI, S6 MJ. Tau protein seems not to be a useful routine clinical marker of axonal damage in multiple sclerosis[J]. Mult Scler, 2006, 12(3): 354-356.
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中华神经医学杂志
2010年 第7期

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